Amgen v. Sanofi: A well characterized antigen insufficient for written description of an antibody The humoral response (or antibody‐mediated response) involves B cells that recognize antigens or pathogens that are circulating in the lymph or blood (“ humor” is a medieval term for body fluid). The response follows this chain of events: Antigens bind to B cells. Interleukins or helper T cells costimulate B cells. In most. There are three…